Article
Power matters in closing the phenotyping gap.
Die Naturwissenschaften - 1 May 2007
Meyer Carola W, Elvert Ralf, Scherag André, Ehrhardt Nicole, Gailus-Durner Valerie, Fuchs Helmut, Schäfer Helmut, Hrabé de Angelis Martin, Heldmaier Gerhard, Klingenspor Martin
Abstract excerpt
Much of our understanding of physiology and metabolism is derived from investigating mouse mutants and transgenic mice, and open-access platforms for standardized mouse phenotyping such as the German Mouse Clinic (GMC) are currently viewed as one powerful tool for identifying novel gene-function relationships. Phenotyping or phenotypic screening involves the comparison of wild-type control mice with their mutant...
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