Article
Association of p53 gene mutations with short survival in pancreatic adenocarcinoma.
Japanese journal of cancer research : Gann - 1 Feb 1995
Nakamori S, Yashima K, Murakami Y, Ishikawa O, Ohigashi H, Imaoka S, Yaegashi S, Konishi Y, Sekiya T
Abstract excerpt
Mutations of the p53 gene have been found in a variety of human cancers and are implicated in the biologic functions of cancer. To investigate the clinical implications of p53 mutations in pancreatic adenocarcinoma, we examined the association of mutations of the p53 gene with patients' prognosis...
Topics
- Adenocarcinoma
- Aged
- Base Sequence
- DNA Mutational Analysis
- Female
- Genes, p53
- Humans
- Male
- Middle Aged
- Molecular Sequence Data
- Multivariate Analysis
- Mutation
- Pancreatic Neoplasms
- Polymerase Chain Reaction
- Polymorphism, Single-Stranded Conformational