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Article

Loss of heterozygosity predicts poor survival after resection of pancreatic adenocarcinoma.

Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract - 1 Oct 2008

Franko Jan, Krasinskas Alyssa M, Nikiforova Marina N, Zarnescu Narcis O, Lee Kenneth K W, Hughes Steven J, Bartlett David L, Zeh Herbert J, Moser A James

Abstract excerpt

BACKGROUND: American Joint Committee on Cancer (AJCC) staging for pancreatic adenocarcinoma is a validated predictor of prognosis but insufficiently discriminates postresection survival. We hypothesized that genetic analysis of resected cancers would correlate with tumor biology and postoperative survival. METHODS: Resected pancreatic ductal and ampullary adenocarcinomas (n = 50) were analyzed for loss of...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 18677542
DOI: 10.1007/s11605-008-0577-9

Genes

KRAS
APC
DCC
MDM2
PTEN
SMAD4

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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