Article
Mitochondrial genetic polymorphisms do not predict survival in patients with pancreatic cancer.
Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology - 1 Sept 2008
Halfdanarson Thorvardur R, Wang Liang, Bamlet William R, de Andrade Mariza, McWilliams Robert R, Cunningham Julie M, Petersen Gloria M
Abstract excerpt
Pancreatic cancer is a highly lethal malignancy, and the majority of patients succumb to the disease within 2 years. We evaluated the role of variants of mitochondrial DNA and mitochondrial haplogroups in predicting prognosis of patients with pancreatic cancer. A total of 24 mitochondrial single nucleotide polymorphisms were genotyped in 990 patients with pancreatic cancer. After adjusting for covariates and...
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