Article
Stability of Borrelia burgdorferi outer surface protein C under immune selection pressure.
The Journal of infectious diseases - 1 Feb 2000
Hodzic E, Feng S, Barthold S W
Abstract excerpt
Outer surface protein (Osp) C immune pressure during persistent infection with Borrelia burgdorferi was examined in relation to genetic variation of ospC. Mice were infected with clonal B. burgdorferi sensu stricto (s.s.) N40 or B. afzelii PKo and then were hyperimmunized with homologous recombinant OspC or with decorin-binding protein A (DbpA) (controls). After 6 months, B. burgdorferi isolates were subjected to...
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