Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Human papillomavirus DNA and p53 status in stage IB bulky cervical cancer.

Journal of cancer research and clinical oncology - 1 Jan 1994

Chen C A, Chen T M, Wu C C, Chang C F, Hsieh C Y

Abstract excerpt

We used the polymerase chain reaction (PCR) to study the presence and typing of human papillomavirus (HPV) DNA, and PCR/single-strand confirmation polymorphism to survey the mutations of the p53 gene in exons 5-9 in 26 bulky stage IB cervical cancers. The HPV DNA was present in 20 out of the 21 (95%) squamous-cell carcinoma tissues, including 13 cases of HPV-16, 0 case of HPV-18, and 7 cases of other HPV types....

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Base Sequence
Share to DNA, Viral
Share to Genes, p53

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Molecular Sequence Data

Share to Mutation

Share to Polymerase Chain Reaction

Share to Polymorphism, Single-Stranded Conformational

Share to Prognosis

Source

Identifiers

PMID: 7962045
DOI: 10.1007/BF01245381

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 8 closest

Human papillomavirus DNA and p53 status in stage IB bulky cervical cancer.PMID 7962045Read ↗

Mutant p53 in patients with invasive cervical cancer stages IB to IIB.Semantic proximity Read ↗

p53 mutations and c-erbB-2 amplification in intraductal and invasive breast carcinomas of high histologic grade.Semantic proximity Read ↗

HPV-negative Squamous Cell Carcinomas of the Cervix With Special Focus on Intraepithelial Precursor Lesions.Semantic proximity Read ↗

Frequent occurrence of p53 gene mutations in uterine cancers at advanced clinical stage and with aggressive histological phenotypes.Semantic proximity Read ↗

Pathogenetic significance of p53 and c-Ki-ras gene mutations and human papillomavirus DNA integration in adenocarcinoma of the uterine cervix and uterine isthmus.Semantic proximity Read ↗

HPV-18 is a poor prognostic factor, unlike the HPV viral load, in patients with stage IB-IIA cervical cancer undergoing radical hysterectomy.Semantic proximity Read ↗

Clinical, morphologic and molecular heterogeneity of HPV-associated oropharyngeal cancerSemantic proximity Read ↗

HPV prevalence and genotypes in different histological subtypes of cervical adenocarcinoma, a worldwide analysis of 760 cases.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.