Human papillomavirus DNA and p53 status in stage IB bulky cervical cancer.

doi:10.1007/BF01245381

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Article

Human papillomavirus DNA and p53 status in stage IB bulky cervical cancer.

Journal of cancer research and clinical oncology - 1 Jan 1994

Chen C A, Chen T M, Wu C C, Chang C F, Hsieh C Y

Abstract excerpt

We used the polymerase chain reaction (PCR) to study the presence and typing of human papillomavirus (HPV) DNA, and PCR/single-strand confirmation polymorphism to survey the mutations of the p53 gene in exons 5-9 in 26 bulky stage IB cervical cancers. The HPV DNA was present in 20 out of the 21 (...

Topics

Adenocarcinoma
Adult
Base Sequence
Carcinoma, Squamous Cell
DNA, Viral
Female
Genes, p53
Humans
Lymphatic Metastasis
Middle Aged
Molecular Sequence Data
Mutation
Neoplasm Staging
Papillomaviridae
Polymerase Chain Reaction
Polymorphism, Single-Stranded Conformational
Prognosis
Uterine Cervical Neoplasms

Source

Open in PubMed

Identifiers

PMID: 7962045
DOI: 10.1007/BF01245381

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-7962045-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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