Article
The involvement of HLA -DRB1*, DQA1*, DQB1* and complement C4A loci in diagnosing systemic lupus erythematosus among Tunisians.
Annals of Saudi medicine - 1 Jan 2000
Ayed Khaled, Gorgi Yousr, Ayed-Jendoubi Saloua, Bardi Rafika
Abstract excerpt
BACKGROUND: Genetic susceptibility to systemic lupus erythematosus (SLE) varies among populations. Few data exist on associations of HLA class II and class III alleles of the major histocompatibility complex (MHC) and susceptibility to SLE in Tunisians. PATIENTS AND METHODS: We compared HLA-DRB1*, DQA1, DQB1* and C4 allotypes in 62 Tunisian SLE patients and 100 matched controls. We also assessed the association...
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