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Article

Mutational study at Ser300 position of the Escherichia coli lactose repressor.

Biochemical and biophysical research communications - 6 Apr 1995

Miura-Onai S, Yabuta M, Ohsuye K

Abstract excerpt

We have previously reported that a Ser300Asn mutant of the Escherichia coli lactose repressor protein produced a temperature-sensitive phenotype. In order to analyze the structure-function relationship of the lactose repressor protein, we conducted 18 amino acid substitutions at this Ser 300 site by using in vitro mutagenesis. The substitutions at this position that exhibited repressors with the wild-type...

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Identifiers

PMID: 7726826
DOI: 10.1006/bbrc.1995.1479

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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