Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Human general transcription factor TFIIA: characterization of a cDNA encoding the small subunit and requirement for basal and activated transcription.

Proceedings of the National Academy of Sciences of the United States of America - 11 Apr 1995

DeJong J, Bernstein R, Roeder R G

Abstract excerpt

The human general transcription factor TFIIA is one of several factors involved in specific transcription by RNA polymerase II, possibly by regulating the activity of the TATA-binding subunit (TBP) of TFIID. TFIIA purified from HeLa extracts consists of 35-, 19-, and 12-kDa subunits. Here we describe the isolation of a cDNA clone (hTFIIA gamma) encoding the 12-kDa subunit. Using expression constructs derived from...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Amino Acid Sequence
Share to Base Sequence

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to DNA-Binding Proteins

Share to Molecular Sequence Data

Share to Mutation

Share to Sequence Homology, Amino Acid

Share to Transcription Factors

Share to Transcription, Genetic

Source

Open in PubMed Open full text

Identifiers

PMID: 7724559
DOI: 10.1073/pnas.92.8.3313
PMCID: PMC42156

Genes

TBP

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Human general transcription factor TFIIA: characterization of a cDNA encoding the small subunit and requirement for basal and activated transcription.PMID 7724559Read ↗

Human TAFII105 Is a Cell Type–Specific TFIID Subunit Related to hTAFII130Semantic proximity Read ↗

Uncleaved TFIIA is a substrate for taspase 1 and active in transcription.Semantic proximity Read ↗

Proteomics of the eukaryotic transcription machinery: identification of proteins associated with components of yeast TFIID by multidimensional mass spectrometry.Semantic proximity Read ↗

Direct interaction of human TFIID with the HIV-1 transactivator tat.Semantic proximity Read ↗

Architecture of TAF11/TAF13/TBP complex suggests novel regulatory state in General Transcription Factor TFIID functionSemantic proximity Read ↗

Unique TATA-binding protein-containing complexes and cofactors involved in transcription by RNA polymerases II and III.Semantic proximity Read ↗

Human TAF(II)135 potentiates transcriptional activation by the AF-2s of the retinoic acid, vitamin D3, and thyroid hormone receptors in mammalian cells.Semantic proximity Read ↗

Cloning and characterization of an evolutionarily divergent DNA-binding subunit of mammalian TFIIIC.Semantic proximity Read ↗

Two Novel <i>Drosophila</i> TAF<sub>II</sub>s Have Homology with Human TAF<sub>II</sub>30 and Are Differentially Regulated during DevelopmentSemantic proximity Read ↗

Novel dimerization fold of RAP30/RAP74 in human TFIIF at 1.7 A resolution.Semantic proximity Read ↗

RNA polymerase B (II) and general transcription factors.Semantic proximity Read ↗

Analysis of the role of TFIIE in transcriptional regulation through structure-function studies of the TFIIEbeta subunit.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.