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Article

Human general transcription factor TFIIA: characterization of a cDNA encoding the small subunit and requirement for basal and activated transcription.

Proceedings of the National Academy of Sciences of the United States of America - 11 Apr 1995

DeJong J, Bernstein R, Roeder R G

Abstract excerpt

The human general transcription factor TFIIA is one of several factors involved in specific transcription by RNA polymerase II, possibly by regulating the activity of the TATA-binding subunit (TBP) of TFIID. TFIIA purified from HeLa extracts consists of 35-, 19-, and 12-kDa subunits. Here we desc...

Topics

Amino Acid Sequence
Base Sequence
DNA, Complementary
DNA-Binding Proteins
Gene Library
Humans
Molecular Sequence Data
Mutation
Protein Binding
Recombinant Proteins
Sequence Homology, Amino Acid

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

TATA Box

TATA-Box Binding Protein

Transcription Factor TFIIA

Transcription Factors

Transcription, Genetic

Source

Open in PubMed Open full text

Identifiers

PMID: 7724559
DOI: 10.1073/pnas.92.8.3313
PMCID: PMC42156

Genes

TBP

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-7724559-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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Human general transcription factor TFIIA: characterization of a cDNA encoding the small subunit and requirement for basal and activated transcription.PMID 7724559Read ↗

Human TAFII105 Is a Cell Type–Specific TFIID Subunit Related to hTAFII130Semantic proximity Read ↗

Uncleaved TFIIA is a substrate for taspase 1 and active in transcription.Semantic proximity Read ↗

Proteomics of the eukaryotic transcription machinery: identification of proteins associated with components of yeast TFIID by multidimensional mass spectrometry.Semantic proximity Read ↗

Direct interaction of human TFIID with the HIV-1 transactivator tat.Semantic proximity Read ↗

Architecture of TAF11/TAF13/TBP complex suggests novel regulatory state in General Transcription Factor TFIID functionSemantic proximity Read ↗

Unique TATA-binding protein-containing complexes and cofactors involved in transcription by RNA polymerases II and III.Semantic proximity Read ↗

Human TAF(II)135 potentiates transcriptional activation by the AF-2s of the retinoic acid, vitamin D3, and thyroid hormone receptors in mammalian cells.Semantic proximity Read ↗

Cloning and characterization of an evolutionarily divergent DNA-binding subunit of mammalian TFIIIC.Semantic proximity Read ↗

Two Novel <i>Drosophila</i> TAF<sub>II</sub>s Have Homology with Human TAF<sub>II</sub>30 and Are Differentially Regulated during DevelopmentSemantic proximity Read ↗

Novel dimerization fold of RAP30/RAP74 in human TFIIF at 1.7 A resolution.Semantic proximity Read ↗

RNA polymerase B (II) and general transcription factors.Semantic proximity Read ↗

Analysis of the role of TFIIE in transcriptional regulation through structure-function studies of the TFIIEbeta subunit.Semantic proximity Read ↗

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