Article
Evidence for an in vivo superantigenic activity in human immunodeficiency virus-infected individuals.
Blood - 15 Sept 1996
Garcia S, Dadaglio G, Cilote V, Chenal H, Bondurand A, Gougeon M L
Abstract excerpt
In a previous study, we reported the existence of a specific anergy affecting selectively the V beta 8 subset in both CD4 and CD8 T cells from human immunodeficiency virus (HIV)-infected persons. Because this observation gives evidence for a previous in vivo activation of this subset by a superantigen, we further characterize, in the present study, this V beta 8-anergy associated with HIV infection. Molecular T...
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