Article
Functional inactivation of Dermatophagoides spp. (house dust mite) reactive human T-cell clones.
Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology - 1 Mar 1991
O'Hehir R E, Aguilar B A, Schmidt T J, Gollnick S O, Lamb J R
Abstract excerpt
Staphylococcal enterotoxins are able both to stimulate powerful polyclonal proliferative responses and to induce non-responsiveness of T lymphocytes expressing the appropriate T-cell antigen receptor V beta gene products. T-cell clones representative of the human response to house dust mite were identified that express either V beta 3 or V beta 6 gene products. The specificity of the latter was confirmed by...
Topics
- Animals
- Clone Cells
- Enterotoxins
- Humans
- Lymphocyte Activation
- Mites
- Phenotype
- Receptors, Antigen, T-Cell
- Receptors, Antigen, T-Cell, alpha-beta
- Staphylococcus aureus
