Article
Mosaicism in Human Epithelium: Macroscopic Monoclonal Patches Cover the Urothelium
1 May 1995
Abstract excerpt
Previous studies of chimeric animals and human tissues have shown the clonal nature of organ development, giving clues as to the normal development of organs and also to abnormal developments, such as atheromatous plaques. The clonal nature of bladder cancer in female patients has been demonstrated, but little has been known of the clonal development of the normal urothelium. Using an X chromosome inactivation...
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