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Article

The human urothelium consists of multiple clonal units, each maintained by a stem cell

30 May 2011

Abstract excerpt

Little is known about the clonal architecture of human urothelium. It is likely that urothelial stem cells reside within the basal epithelial layer, yet lineage tracing from a single stem cell as a means to show the presence of a urothelial stem cell has never been performed. Here, we identify clonally related cell areas within human bladder mucosa in order to visualize epithelial fields maintained by a single...

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PMID: 21744343
DOI: 10.1002/path.2945

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