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Article

Genetic alterations in thyroid hyperfunctioning adenomas.

The Journal of clinical endocrinology and metabolism - 1 Apr 1995

Russo D, Arturi F, Wicker R, Chazenbalk G D, Schlumberger M, DuVillard J A, Caillou B, Monier R, Rapoport B, Filetti S

Abstract excerpt

Thirty-seven thyroid autonomously hyperfunctioning adenomas were screened for mutations in the TSH receptor (TSHR), G alpha s (gsp), and ras genes. Polymerase chain reaction-amplified fragments of the TSHR C-terminal part (exon 10), the G alpha s (exons 8 and 9), and the three ras genes were obtained from the genomic DNA extracted from 37 tumors and their adjacent normal tissues and were studied by direct...

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Source

Identifiers

PMID: 7714109
DOI: 10.1210/jcem.80.4.7714109

Genes

TSHR

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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