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Article

Transvection and silencing of the Scr homeotic gene of Drosophila melanogaster.

Genetics - 1 Jun 2002

Southworth Jeffrey W, Kennison James A

Abstract excerpt

The Sex combs reduced (Scr) gene specifies the identities of the labial and first thoracic segments in Drosophila melanogaster. In imaginal cells, some Scr mutations allow cis-regulatory elements on one chromosome to stimulate expression of the promoter on the homolog, a phenomenon that was named transvection by Ed Lewis in 1954. Transvection at the Scr gene is blocked by rearrangements that disrupt pairing, but...

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Identifiers

PMID: 12072469
DOI: 10.1093/genetics/161.2.733
PMCID: PMC1462157

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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