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Article

A functional and structural analysis of the Sex combs reduced locus of Drosophila melanogaster.

Genetics - 1 Oct 1991

Pattatucci A M, Otteson D C, Kaufman T C

Abstract excerpt

We have undertaken a developmental genetic analysis of the homeotic gene Sex combs reduced (Scr) of Drosophila melanogaster by examining embryonic and adult phenotypes of mutations affecting Scr gene function. Molecular mapping of Scr breakpoint lesions has defined a segment of greater than 70 kb...

Topics

Alleles
Animals
Crosses, Genetic
Drosophila Proteins
Drosophila melanogaster
Female
Gene Expression Regulation
Genes, Lethal
Genetic Complementation Test
Insect Hormones
Male
Mutation

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Phenotype

Recombination, Genetic

Restriction Mapping

Temperature

Transcription Factors

Source

Open in PubMed Open full text

Identifiers

PMID: 1743486
DOI: 10.1093/genetics/129.2.423
PMCID: PMC1204634

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-1743486-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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A functional and structural analysis of the Sex combs reduced locus of Drosophila melanogaster.PMID 1743486Read ↗

The homeotic gene Sex combs reduced of Drosophila melanogaster is differentially regulated in the embryonic and imaginal stages of development.Semantic proximity Read ↗

Analysis of the sequence and phenotype of Drosophila Sex combs reduced alleles reveals potential functions of conserved protein motifs of the Sex combs reduced protein.Semantic proximity Read ↗

Identification of Polycomb and trithorax group responsive elements in the regulatory region of the Drosophila homeotic gene Sex combs reduced.Semantic proximity Read ↗

Transvection and silencing of the Scr homeotic gene of Drosophila melanogaster.Semantic proximity Read ↗

Molecular characterization of Cephalothorax, the Tribolium ortholog of Sex combs reduced.Semantic proximity Read ↗

Genetic characterization of the role of the two HOX proteins, Proboscipedia and Sex Combs Reduced, in determination of adult antennal, tarsal, maxillary palp and proboscis identities in Drosophila melanogaster.Semantic proximity Read ↗

A Distalless-responsive enhancer of the Hox gene Sex combs reduced is required for segment- and sex-specific sensory organ development in Drosophila.Semantic proximity Read ↗

Acquisition of a leucine zipper motif as a mechanism of antimorphy for an allele of the Drosophila Hox gene Sex combs reduced.Semantic proximity Read ↗

The Tribolium castaneum ortholog of Sex combs reduced controls dorsal ridge development.Semantic proximity Read ↗

The mouse Hox-1.3 gene is functionally equivalent to the Drosophila Sex combs reduced gene.Semantic proximity Read ↗

A genetic screen for modifiers of Deformed homeotic function identifies novel genes required for head development.Semantic proximity Read ↗

Effects of hypo-O-GlcNAcylation on Drosophila development.Semantic proximity Read ↗

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