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Article

fog-1, a regulatory gene required for specification of spermatogenesis in the germ line of Caenorhabditis elegans.

Genetics - 1 May 1990

Barton M K, Kimble J

Abstract excerpt

In wild-type Caenorhabditis elegans, the XO male germ line makes only sperm and the XX hermaphrodite germ line makes sperm and then oocytes. In contrast, the germ line of either a male or a hermaphrodite carrying a mutation of the fog-1 (feminization of the germ line) locus is sexually transformed: cells that would normally make sperm differentiate as oocytes. However, the somatic tissues of fog-1 mutants remain...

Topics

Alleles
Animals
Caenorhabditis
Chromosome Mapping
Epistasis, Genetic
Female
Genes
Genes, Regulator
Genotype
Male
Mutation
Organ Specificity

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Phenotype

Sex Determination Analysis

Spermatogenesis

Temperature

Source

Open in PubMed Open full text

Identifiers

PMID: 2341035
DOI: 10.1093/genetics/125.1.29
PMCID: PMC1204007

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-2341035-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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