Article
GLD-3 and control of the mitosis/meiosis decision in the germline of Caenorhabditis elegans.
Genetics - 1 Sept 2004
Eckmann Christian R, Crittenden Sarah L, Suh Nayoung, Kimble Judith
Abstract excerpt
Germ cells can divide mitotically to replenish germline tissue or meiotically to produce gametes. In this article, we report that GLD-3, a Caenorhabditis elegans Bicaudal-C homolog, promotes the transition from mitosis to meiosis together with the GLD-2 poly(A) polymerase. GLD-3 binds GLD-2 via a small N-terminal region present in both GLD-3S and GLD-3L isoforms, and GLD-2 and GLD-3 can be co-immunoprecipitated...
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