Article
Resistance of Neisseria gonorrhoeae to antimicrobial hydrophobic agents is modulated by the mtrRCDE efflux system.
Microbiology (Reading, England) - 1 Mar 1995
Hagman K E, Pan W, Spratt B G, Balthazar J T, Judd R C, Shafer W M
Abstract excerpt
The mtr (multiple transferable resistance) system of Neisseria gonorrhoeae determines levels of gonococcal resistance to hydrophobic agents (HAs), including detergent-like fatty acids and bile salts that bathe certain mucosal surfaces. The genetic organization of the mtr system was determined and...
Topics
- Amino Acid Sequence
- Bacterial Proteins
- Base Sequence
- Cloning, Molecular
- DNA Primers
- DNA, Bacterial
- Drug Resistance, Multiple
- Escherichia coli
- Ferredoxin-NADP Reductase
- Genes, Bacterial
- Lipoproteins
- Molecular Sequence Data
- Mutation
- Neisseria gonorrhoeae
- Pseudomonas aeruginosa
- Repressor Proteins
- Sequence Homology, Amino Acid