Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Resistance of Neisseria gonorrhoeae to antimicrobial hydrophobic agents is modulated by the mtrRCDE efflux system.

Microbiology (Reading, England) - 1 Mar 1995

Hagman K E, Pan W, Spratt B G, Balthazar J T, Judd R C, Shafer W M

Abstract excerpt

The mtr (multiple transferable resistance) system of Neisseria gonorrhoeae determines levels of gonococcal resistance to hydrophobic agents (HAs), including detergent-like fatty acids and bile salts that bathe certain mucosal surfaces. The genetic organization of the mtr system was determined and found to consist of the mtrR gene, which encodes a transcriptional regulator (MtrR), and three tandemly linked genes...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Amino Acid Sequence
Share to Bacterial Proteins

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Base Sequence

Share to Cloning, Molecular

Share to DNA Primers

Share to Escherichia coli

Share to Molecular Sequence Data

Share to Mutation

Source

Identifiers

PMID: 7711899
DOI: 10.1099/13500872-141-3-611

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Resistance of Neisseria gonorrhoeae to antimicrobial hydrophobic agents is modulated by the mtrRCDE efflux system.PMID 7711899Read ↗

Identification of a cell envelope protein (MtrF) involved in hydrophobic antimicrobial resistance in Neisseria gonorrhoeae.Semantic proximity Read ↗

Involvement of the gonococcal MtrE protein in the resistance of Neisseria gonorrhoeae to toxic hydrophobic agents.Semantic proximity Read ↗

Clinically relevant mutations that cause derepression of the Neisseria gonorrhoeae MtrC-MtrD-MtrE Efflux pump system confer different levels of antimicrobial resistance and in vivo fitness.Semantic proximity Read ↗

Transcriptional control of the mtr efflux system of Neisseria gonorrhoeae.Semantic proximity Read ↗

Induction of the mtrCDE-encoded efflux pump system of Neisseria gonorrhoeae requires MtrA, an AraC-like protein.Semantic proximity Read ↗

Mechanistic Basis for Decreased Antimicrobial Susceptibility in a Clinical Isolate of Neisseria gonorrhoeae Possessing a Mosaic-Like mtr Efflux Pump LocusSemantic proximity Read ↗

The farAB-encoded efflux pump mediates resistance of gonococci to long-chained antibacterial fatty acids.Semantic proximity Read ↗

Mechanistic basis for decreased antimicrobial susceptibility in a clinical isolate of <i>Neisseria gonorrhoeae</i> possessing a mosaic-like <i>mtr</i> efflux pump locusSemantic proximity Read ↗

Transcriptional regulation of the mtrCDE efflux pump operon: importance for Neisseria gonorrhoeae antimicrobial resistanceSemantic proximity Read ↗

Loss-of-function mutations in the mtr efflux system of Neisseria gonorrhoeaeSemantic proximity Read ↗

The MtrR repressor binds the DNA sequence between the mtrR and mtrC genes of Neisseria gonorrhoeae.Semantic proximity Read ↗

Structures of Neisseria gonorrhoeae MtrR-operator complexes reveal molecular mechanisms of DNA recognition and antibiotic resistance-conferring clinical mutations.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.