Article
Mutation of cell cycle regulators and their impact on superficial bladder cancer.
The Urologic clinics of North America - 1 Feb 2000
Rabbani F, Cordon-Cardo C
Abstract excerpt
Early cytogenetic studies in bladder cancer identify regions of chromosomal gain or loss that can be candidate loci for oncogenes and tumor suppressor genes. Oncogenes with potential prognostic significance identified in bladder cancer the RAS family, epidermal growth factor receptor, ERBB-2, MDM2, and cyclin D1. The TP53 gene has been the most thoroughly characterized tumor suppressor gene in bladder cancer,...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
