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Article

Human autoantibody recognition of DNA.

28 Mar 1995

Abstract excerpt

Combinatorial IgG Fab phage display libraries prepared from a systemic lupus erythematosus (SLE) donor and a healthy donor were affinity selected against human placental DNA. Human monoclonal antibody Fab fragments specific for DNA were isolated from both libraries, although Fabs of the highest affinity were isolated only from the lupus library. Generally, apparent affinities of the Fabs for human placental DNA,...

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Identifiers

PMID: 7708679
DOI: 10.1073/pnas.92.7.2529

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Source receipt: pubmed, retrieved 7 Sept 2026.

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