Article
Characterization of a specific interaction between Escherichia coli thymidylate synthase and Escherichia coli thymidylate synthase mRNA.
Nucleic acids research - 11 Mar 1995
Voeller D M, Changchien L M, Maley G F, Maley F, Takechi T, Turner R E, Montfort W R, Allegra C J, Chu E
Abstract excerpt
Previous studies have shown that human TS mRNA translation is controlled by a negative autoregulatory mechanism. In this study, an RNA electrophoretic gel mobility shift assay confirmed a direct interaction between Escherichia coli (E.coli) TS protein and its own E.coli TS mRNA. Two cis-acting sequences in the E.coli TS mRNA protein-coding region were identified, with one site corresponding to nucleotides 207-460...
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