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Article

A germline insertion in the tuberous sclerosis (Tsc2) gene gives rise to the Eker rat model of dominantly inherited cancer

1 Jan 1995

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Share to Renal and related cancers
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Identifiers

PMID: 7704028
DOI: 10.1038/ng0195-70

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Related research

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Click a neighbor to travelStep 1 · 12 closest

A germline insertion in the tuberous sclerosis (Tsc2) gene gives rise to the Eker rat model of dominantly inherited cancerPMID 7704028Read ↗

TSC2 gene mutant (Eker) rat model of a Mendelian dominantly inherited cancer.Semantic proximity Read ↗

The predisposing gene of the Eker rat inherited cancer syndrome is tightly linked to the tuberous sclerosis (TSC2) gene.Semantic proximity Read ↗

[Cancer genetics of TSC2 gene mutant(Eker) rat model].Semantic proximity Read ↗

Identification of tuberous sclerosis 2 messenger RNA splice variants that are conserved and differentially expressed in rat and human tissues.Semantic proximity Read ↗

Mourning Dr. Alfred G. Knudson: the two‐hit hypothesis, tumor suppressor genes, and the tuberous sclerosis complexSemantic proximity Read ↗

Predisposition to renal carcinoma in the Eker rat is determined by germ-line mutation of the tuberous sclerosis 2 (TSC2) gene.Semantic proximity Read ↗

Transgenic expression of the N525S-tuberin variant in Tsc2 mutant (Eker) rats causes dominant embryonic lethality.Semantic proximity Read ↗

A novel TSC2 mutation causing tuberless tuberous sclerosis.Semantic proximity Read ↗

Intragenic Tsc2 somatic mutations as Knudson's second hit in spontaneous and chemically induced renal carcinomas in the Eker rat model.Semantic proximity Read ↗

Renal carcinogenesis: genotype, phenotype and dramatype.Semantic proximity Read ↗

Uterine leiomyoma in the Eker rat: A unique model for important diseases of womenSemantic proximity Read ↗

Allelic loss at the tuberous sclerosis 2 locus in spontaneous tumors in the Eker rat.Semantic proximity Read ↗

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