Article
Self-regulation of 70-kilodalton heat shock proteins in Saccharomyces cerevisiae.
Molecular and cellular biology - 1 Apr 1990
Stone D E, Craig E A
Abstract excerpt
To determine whether the 70-kilodalton heat shock proteins of Saccharomyces cerevisiae play a role in regulating their own synthesis, we studied the effect of overexpressing the SSA1 protein on the activity of the SSA1 5'-regulatory region. The constitutive level of Ssa1p was increased by fusing the SSA1 structural gene to the GAL1 promoter. A reporter vector consisting of an SSA1-lacZ translational fusion was...
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