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Article

Prevalence of CYP2D6 gene duplication and its repercussion on the oxidative phenotype in a white population.

Clinical pharmacology and therapeutics - 1 Mar 1995

Agúndez J A, Ledesma M C, Ladero J M, Benítez J

Abstract excerpt

The occurrence of multiple copies of the CYP2D6 gene was investigated 217 white healthy Spaniards by the combined use of Xba I and Eco RI restriction fragment length polymorphism (RFLP) analyses. About 3.5% of the alleles yielded an 12.1 kb Eco RI-RFLP product in combination with the 42 kb Xba I-RFLP product, which is indicative of multiple CYP2D6. The prevalence of subjects carrying multiple CYP2D6 was 7%. The...

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Identifiers

PMID: 7697944
DOI: 10.1016/0009-9236(95)90151-5

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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