Article
Alcohol dehydrogenase: enzymology and metabolism.
Alcohol and alcoholism (Oxford, Oxfordshire). Supplement - 1 Jan 1994
Yin S J
Abstract excerpt
Alcohol dehydrogenase (ADH), the principal enzyme responsible for ethanol oxidation, constitutes a complex family in humans. Based on structural and kinetic features, ADH can be divided into five classes. Low-Km class I beta-ADH and gamma-ADH show genetic polymorphism among racial populations. The allozymes exhibit distinct maximal activities due to single amino acid exchanges at different sites in the...
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