Article
Nikkomycin Z supersensitivity of an echinocandin-resistant mutant of Saccharomyces cerevisiae.
Antimicrobial agents and chemotherapy - 1 Jan 1995
el-Sherbeini M, Clemas J A
Abstract excerpt
Echinocandins and nikkomycins are antibiotics that inhibit the synthesis of the essential cell wall polysaccharide polymers 1,3-beta-glucan and chitin, respectively. Some 40 echinocandin-resistant Saccharomyces cerevisiae mutants were isolated and assigned to five complementation groups. Four complementation groups contained mutants with 38 recessive mutations. The fifth complementation group comprised mutants...
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