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Article

Hyper-resistance to nitrogen mustard in Saccharomyces cerevisiae is caused by defective choline transport.

Current genetics - 1 Jun 1991

Li Z Y, Haase E, Brendel M

Abstract excerpt

The recessive hnm1 mutant allele is responsible for hyper-resistance to nitrogen mustard in Saccharomyces cerevisiae. Transformation with a single-copy HNM1 wild-type allele of such hyper-resistant mutants will restore wild-type sensitivity to nitrogen mustard. By contrast the presence of multi-copy vectors containing HNM1, in either a hyper-resistant hnm1 mutant or an HNM1 wild-type, will lead to a novel,...

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PMID: 1878995
DOI: 10.1007/BF00312732

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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