Low-dose recombinant interferon therapy in anti-HBe-positive chronic hepatitis B in Asian Indians.

doi:10.1111/j.1440-1746.1998.tb00712.x

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Back to search

Article

Low-dose recombinant interferon therapy in anti-HBe-positive chronic hepatitis B in Asian Indians.

Journal of gastroenterology and hepatology - 1 Jul 1998

Guptan R C, Thakur V, Malhotra V, Sarin S K

Abstract excerpt

Approximately 15% of Indian patients with hepatitis B virus (HBV)-related chronic liver disease (CLD) have infection with precore mutant forms. These patients are likely to have an aggressive course. There are equivocal reports of success with interferon therapy of mutant infection in the West. T...

Topics

Adult
Antiviral Agents
Case-Control Studies
DNA, Viral
Female
Hepatitis B Antibodies
Hepatitis B Surface Antigens
Hepatitis B e Antigens
Hepatitis B virus
Hepatitis B, Chronic
Humans
India

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Interferon alpha-2

Interferon-alpha

Male

Middle Aged

Mutation

Recombinant Proteins

Source

Open in PubMed

Identifiers

PMID: 9715416
DOI: 10.1111/j.1440-1746.1998.tb00712.x

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-9715416-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

Community interpretation

Discuss the evidence

Ask a question, add context or challenge an interpretation. Community activity is separate from scientific evidence strength.

discussions

replies

Citations encouraged

Claims remain attributable.

No discussion yet

Be the first to add a careful, cited interpretation.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Low-dose recombinant interferon therapy in anti-HBe-positive chronic hepatitis B in Asian Indians.PMID 9715416Read ↗

Hepatitis B virus unable to secrete e antigen and response to interferon in chronic hepatitis B.Semantic proximity Read ↗

Absence of hepatitis B virus precore mutants in patients with chronic hepatitis B responding to interferon-alpha.Semantic proximity Read ↗

Lamivudine and alpha-interferon in combination long term for precore mutant chronic hepatitis B.Semantic proximity Read ↗

Randomized controlled trial of recombinant interferon-alpha 2b in the treatment of Chinese patients with chronic hepatitis C.Semantic proximity Read ↗

Early reduction of infected hepatocytes by activated immunity at the time of interferon withdrawal hepatitis followed by lamivudine administration resulted in higher seroconversion in hepatitis Be antigen-positive patients with chronic hepatitis B.Semantic proximity Read ↗

Analysis of clinical, biochemical and viral factors associated with early relapse after lamivudine treatment for hepatitis B e antigen-negative chronic hepatitis B patients in Taiwan.Semantic proximity Read ↗

Reactivation of precore mutant hepatitis B virus leading to fulminant hepatic failure following cytotoxic treatment.Semantic proximity Read ↗

Efficacy of 6-month interferon therapy in chronic hepatitis B virus infection in Japan.Semantic proximity Read ↗

Efficacy of human leucocyte alpha-interferon treatment for chronic hepatitis C virus infection.Semantic proximity Read ↗

Relationship between the serum alanine aminotransferase level at the end of interferon treatment and histologic changes in wild-type and precore mutant hepatitis B virus infections.Semantic proximity Read ↗

Efficacy of human leucocyte alpha-interferon treatment for chronic hepatitis C virus infection.Semantic proximity Read ↗

Decrease of wild-type and precore mutant duck hepatitis B virus replication during lamivudine treatment in white Pekin ducks infected with the viruses.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.