Article
Grouping of class I HLA alleles using electrostatic distribution maps of the peptide binding grooves.
Methods in molecular biology (Clifton, N.J.) - 1 Jan 2007
Kangueane Pandjassarame, Sakharkar Meena Kishore
Abstract excerpt
Human leukocyte antigen (HLA) molecules involved in immune function by binding to short peptides (8-20 residues) have different sequences in different individuals belonging to distinct ethnic population. Hence, the peptide-binding function of HLA alleles is specific. Class I HLA alleles (alternative forms of a gene) are associated with CD8+ T cells, and their allele-specific sequence information is available at...
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