Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Differentiation-dependent differences in murine T cell susceptibility to negative regulation by the lung.

American journal of respiratory cell and molecular biology - 1 May 2011

Busick Rhea Y, Yammani Rama D, Alexander-Miller Martha A

Abstract excerpt

A large number of viral infections are contracted via the respiratory route. Thus, an effective immune response at this site is of vital importance. Past studies in murine models analyzing a number of viruses have reported that CD8(+) effector T cells entering the lung after respiratory infection exhibit significant functional inactivation. The impaired function in these cells has been proposed to be the result...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Bronchoalveolar Lavage
Share to CD8-Positive T-Lymphocytes

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Hemagglutinins

Share to Immunologic Memory

Share to Interferon-gamma

Share to Mice, Inbred BALB C

Share to T-Lymphocytes

Source

Open in PubMed Open full text

Identifiers

PMID: 21216971
DOI: 10.1165/rcmb.2010-0377OC
PMCID: PMC3095980

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Differentiation-dependent differences in murine T cell susceptibility to negative regulation by the lung.PMID 21216971Read ↗

Acute Viral Respiratory Infection Rapidly Induces a CD8+ T Cell Exhaustion-like Phenotype.Semantic proximity Read ↗

Partitioning of responder CD8+ T cells in lymph node and lung of mice with Sendai virus pneumonia by LECAM-1 and CD45RB phenotype.Semantic proximity Read ↗

Lung natural killer cells in mice: phenotype and response to respiratory infection.Semantic proximity Read ↗

Efficacious control of cytomegalovirus infection after long-term depletion of CD8+ T lymphocytesSemantic proximity Read ↗

Critical Role for CD4+T Cells in Controlling Retrovirus Replication and Spread in Persistently Infected MiceSemantic proximity Read ↗

CD8+ T Cells Prevent Lethality from Neonatal Murine Roseolovirus InfectionSemantic proximity Read ↗

Coinfection with Streptococcus pneumoniae Negatively Modulates the Size and Composition of the Ongoing Influenza-Specific CD8+ T Cell ResponseSemantic proximity Read ↗

Alveolar macrophages regulate the induction of primary cytotoxic T-lymphocyte responses during influenza virus infection.Semantic proximity Read ↗

Division-linked differentiation can account for CD8+ T-cell phenotype in vivo.Semantic proximity Read ↗

Mouse lung and spleen natural killer cells have phenotypic and functional differences, in part influenced by macrophages.Semantic proximity Read ↗

Predicting CD62L expression during the CD8+ T-cell response in vivo.Semantic proximity Read ↗

Alveolar Macrophages Prevent Lethal Influenza Pneumonia By Inhibiting Infection Of Type-1 Alveolar Epithelial Cells.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.