Article
Ribosome activity and modification of 16S RNA are influenced by deletion of ribosomal protein S20.
Molecular microbiology - 1 Mar 1993
Rydén-Aulin M, Shaoping Z, Kylsten P, Isaksson L A
Abstract excerpt
A spontaneous mutant of Escherichia coli K-12 was isolated that shows an increased misreading ability of all three nonsense codons together with an inability to grow at 42 degrees C. It is demonstrated that the mutation is a deletion of the gene rpsT, coding for ribosomal protein S20. The loss of this protein not only influences the decoding properties of the ribosome; the modification pattern of 16S ribosomal...
Topics
- Bacterial Proteins
- Codon
- Escherichia coli
- Gene Deletion
- Genes, Bacterial
- Genes, Lethal
- Genes, Suppressor
- Mutation
- Peptide Chain Termination, Translational
- Protein Biosynthesis
- RNA, Bacterial