Article
Escherichia coli 30S mutants lacking protein S20 are defective in translation initiation.
Biochimica et biophysica acta - 27 Aug 1990
Götz F, Dabbs E R, Gualerzi C O
Abstract excerpt
The 30S ribosomal subunits derived from Escherichia coli TA114, a a temperature-sensitive mutant lacking ribosomal protein S20, were shown to be defective in two ways: (a) they have a reduced capacity for association with the 50S ribosomal subunit which results in the impairment of most of the functions requiring a coordinated interaction between the two subunits; (b) they are defective in functions which do not...
Topics
- Kinetics
- Mutation
- Peptide Biosynthesis
- Peptide Chain Initiation, Translational
- Peptides
- Poly U
- RNA, Transfer, Amino Acyl
- Ribosomal Proteins
- Ribosomes
- Temperature