Article
Study of the function of Escherichia coli ribosomal RNA through site-directed mutagenesis.
Biochemistry and cell biology = Biochimie et biologie cellulaire - 1 Jan 1990
Leclerc D, Brakier-Gingras L
Abstract excerpt
Various approaches have been developed to study how mutations in Escherichia coli ribosomal RNA affect the function of the ribosome. Most of them are in vivo approaches, where mutations are introduced in a specialized plasmid harboring the ribosomal RNA genes. The mutated plasmids are then expres...
Topics
- Base Sequence
- Drug Resistance, Microbial
- Escherichia coli
- Genes, Bacterial
- Molecular Sequence Data
- Mutation
- Nucleic Acid Conformation
- RNA, Bacterial
- RNA, Ribosomal
- Ribosomes
