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Article

Distinct hypomyelinated phenotypes in MBP-SV40 large T transgenic mice.

Journal of neuroscience research - 15 Feb 1993

Jensen N A, Smith G M, Shine H D, Garvey J S, Hood L

Abstract excerpt

To study the effect of SV40 large T-antigen expression in myelin-forming cells of both the central and peripheral nervous system, a series of transgenic mice were generated expressing the SV40 large T-antigen under control of the myelin basic protein (MBP) promoter. Two neurologic phenotypes, designated A and B, appeared among individual transgenic founders and their progeny. The A mice developed a severe action...

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Source

Identifiers

PMID: 7681114
DOI: 10.1002/jnr.490340302

Genes

MBP

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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