Article
Molecular phenotype of simian virus 40 large T antigen-induced primitive neuroectodermal tumors in four different lines of transgenic mice.
Laboratory investigation; a journal of technical methods and pathology - 1 Jan 1994
Fung K M, Chikaraishi D M, Suri C, Theuring F, Messing A, Albert D M, Lee V M, Trojanowski J Q
Abstract excerpt
BACKGROUND: We compared the molecular phenotypes of central nervous system tumors arising in four different lines of transgenic mice (TGM) carrying the Simian virus 40 large T antigen driven by different promoters or enhancers. Two of the four lines developed primitive neuroectodermal tumors (PNE...
Topics
- Adrenal Gland Neoplasms
- Animals
- Antigens, Polyomavirus Transforming
- Blotting, Western
- Central Nervous System Neoplasms
- Disease Models, Animal
- Eye Neoplasms
- Glial Fibrillary Acidic Protein
- Immunohistochemistry
- Mice
- Mice, Transgenic
- Microscopy, Electron
- Myelin Basic Protein