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Article

Disturbed oligodendrocyte development and recovery from hypomyelination in a c-myc transgenic mouse mutant.

Journal of neuroscience research - 1 Oct 2001

Orian J M, Ahern A J, Ayers M M, Levine J M, Tapp L D, Reynolds R

Abstract excerpt

The complexity of interactions underlying the elaboration of myelin has been extensively demonstrated. We provide evidence that signals promoting myelination are not confined to the normal developmental time window for myelination and persist well into adult life. The 2-50 mutant, described previously, carries a c-myc transgene regulated by a myelin basic protein promoter. This mutant is characterised by severe...

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PMID: 11599001
DOI: 10.1002/jnr.1196

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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