Article
Dysmyelination in class I MHC transgenic mice.
Microscopy research and technique - 1 Nov 1995
Turnley A M, Morahan G
Abstract excerpt
Why is it that oligodendrocytes do not normally express major histocompatibility complex (MHC) molecules? To examine the effect of aberrant MHC expression in oligodendrocytes, transgenic mice have been produced which expressed the class I MHC gene, H-2Kb, under direction of the MBP promoter [Turn...
Topics
- Animals
- Demyelinating Diseases
- Endoplasmic Reticulum
- Gene Expression Regulation
- Genes, MHC Class I
- Mice
- Mice, Neurologic Mutants
- Mice, Transgenic
- Oligodendroglia
- Phenotype