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Article

Progressive hind limb paralysis in mice carrying a v-Mos transgene.

Journal of neuropathology and experimental neurology - 1 Sept 1992

Propst F, Cork L C, Kovatch R M, Kasenally A B, Wallace R, Rosenberg M P

Abstract excerpt

To study the function of the protooncogene Mos in mouse brain development we have created a transgenic mouse model system in which an activated form of the gene, the murine retroviral v-Mos gene, is highly overexpressed in the brain. Six transgenic founder animals and mice of one established transgenic line (line TG66) displayed a progressive hind limb paralysis with onset between 18 days and 9 months. The...

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Identifiers

PMID: 1381415
DOI: 10.1097/00005072-199209000-00004

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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