Article
CD4+ human immunodeficiency virus type 1 (HIV-1) envelope-specific cytotoxic T lymphocytes derived from the peripheral blood cells of an HIV-1-infected individual.
AIDS research and human retroviruses - 1 Jan 1993
Curiel T J, Wong J T, Gorczyca P F, Schooley R T, Walker B D
Abstract excerpt
Virus-specific cytotoxic T lymphocytes (CTL) are frequently of the CD8+ surface phenotype, although CTL of the CD4+ surface phenotype have also been described. Published reports of CTL derived from peripheral blood mononuclear cells (PBMC) of individuals infected with human immunodeficiency virus type 1 (HIV-1) have described primarily cells of the CD8+ surface phenotype. However, CD4+ HIV-1 envelope-specific CTL...
Topics
- CD4 Antigens
- Cell Line
- Epitopes
- Gene Products, env
- HIV Infections
- HIV-1
- HLA Antigens
- Humans
- Male
- Phenotype
- T-Lymphocyte Subsets