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Article

Differential neutralization of human immunodeficiency virus (HIV) replication in autologous CD4 T cells by HIV-specific cytotoxic T lymphocytes.

Journal of virology - 1 Apr 2009

Chen Huabiao, Piechocka-Trocha Alicja, Miura Toshiyuki, Brockman Mark A, Julg Boris D, Baker Brett M, Rothchild Alissa C, Block Brian L, Schneidewind Arne, Koibuchi Tomohiko, Pereyra Florencia, Allen Todd M, Walker Bruce D

Abstract excerpt

Defining the antiviral efficacy of CD8 T cells is important for immunogen design, and yet most current assays do not measure the ability of responses to neutralize infectious virus. Here we show that human immunodeficiency virus (HIV)-specific cytotoxic T-lymphocyte (CTL) clones and cell lines derived from infected persons and targeting diverse epitopes differ by over 1,000-fold in their ability to retard...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Enzyme-Linked Immunosorbent Assay

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Source

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Identifiers

PMID: 19158248
DOI: 10.1128/JVI.02073-08
PMCID: PMC2655558

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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