Article
Antibody mimicking the action of RAS proteins on yeast adenylyl cyclase: implication for RAS-effector interaction.
Molecular and cellular biology - 1 Feb 1993
Suzuki N, Tsujino K, Minato T, Nishida Y, Okada T, Kataoka T
Abstract excerpt
Polyclonal antisera were raised against various subregions of Saccharomyces cerevisiae adenylyl cyclase in order to examine the molecular mechanism of interaction between adenylyl cyclase and RAS proteins. One of the antisera was found to activate adenylyl cyclase to an extent comparable to that activated by saturating amounts of yeast RAS2 protein produced in Escherichia coli. The stimulatory effect of this...
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