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Article

Isolation and Characterization of a Novel Zinc-finger Protein with Transcriptional Repressor Activity

1 Sept 1995

Abstract excerpt

To identify genes that can repress the expression of growth regulatory molecules, a human fetal cDNA library was screened with a degenerate oligonucleotide that corresponds to the conserved stretch of 6 amino acids connecting successive zinc-finger regions in the Wilms' tumor suppressor/Egr-1 family of DNA-binding proteins. One clone, designated zinc-finger protein 174 (ZNF174), corresponds to a putative...

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Share to Congenital Anomalies and Fetal Surgery
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PMID: 7673192
DOI: 10.1074/jbc.270.38.22143

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