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Article

ZC3H4-a novel Cys-Cys-Cys-His-type zinc finger protein-is essential for early embryogenesis in mice†.

Biology of reproduction - 11 Feb 2021

Su Jianmin, Miao Xiaosu, Archambault Danielle, Mager Jesse, Cui Wei

Abstract excerpt

Zinc finger domains of the Cys-Cys-Cys-His (CCCH) class are evolutionarily conserved proteins that bind nucleic acids and are involved in various biological processes. Nearly 60 CCCH-type zinc finger proteins have been identified in humans and mice, most have not been functionally characterized. Here, we provide the first in vivo functional characterization of ZC3H4-a novel CCCH-type zinc finger protein. Our...

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Identifiers

PMID: 33246328
DOI: 10.1093/biolre/ioaa215
PMCID: PMC7876667

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