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Article

Characterization of a Novel KRAB/C2H2Zinc Finger Transcription Factor Involved in Bone Development

1 May 2001

Abstract excerpt

Osteogenic differentiation involves a cascade of coordinated gene expression that regulates cell proliferation and matrix protein formation in a defined temporo-spatial manner. Here we have used differential display to identify a novel zinc finger transcription factor (AJ18) that is induced during differentiation of bone cells in vitro and in vivo. The 64-kDa protein, encoded by a 7- kilobase mRNA, contains a...

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PMID: 11278774
DOI: 10.1074/jbc.m010885200

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