Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Genetic instability within monotonous runs of CpG sequences in Escherichia coli.

Genetics - 1 Jul 1995

Bichara M, Schumacher S, Fuchs R P

Abstract excerpt

Genetic information can be altered by base substitutions, frameshift mutations, and addition or deletion of nucleotides. Deletions represent an important class of genetic aberration occurring at DNA sequences where it is often possible to predict the existence of intermediates of mutation. Instability within tracts of repetitive sequence have recently been associated with several genetic disorders, including the...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Base Sequence
Share to DNA, Bacterial
Share to DNA Transposable Elements

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Escherichia coli

Share to Molecular Sequence Data

Share to Mutation

Share to Plasmids

Share to Repetitive Sequences, Nucleic Acid

Source

Open in PubMed Open full text

Identifiers

PMID: 7672590
DOI: 10.1093/genetics/140.3.897
PMCID: PMC1206674

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Genetic instability within monotonous runs of CpG sequences in Escherichia coli.PMID 7672590Read ↗

Two distinct models account for short and long deletions within sequence repeats in Escherichia coli.Semantic proximity Read ↗

Z-DNA-forming sequences generate large-scale deletions in mammalian cells.Semantic proximity Read ↗

An AP site can protect against the mutagenic potential of 8-oxoG when present within a tandem clustered site in E. coli.Semantic proximity Read ↗

Length of CTG.CAG repeats determines the influence of mismatch repair on genetic instability.Semantic proximity Read ↗

Biological consequences of potential repair intermediates of clustered base damage site in Escherichia coli.Semantic proximity Read ↗

Sticky DNA formation in vivo alters the plasmid dimer/monomer ratio.Semantic proximity Read ↗

Expansion of CTG repeats from human disease genes is dependent upon replication mechanisms in Escherichia coli: the effect of long patch mismatch repair revisited.Semantic proximity Read ↗

Clustered DNA lesion sites as a source of mutations during human colorectal tumourigenesis.Semantic proximity Read ↗

Insights into mutagenesis using Escherichia coli chromosomal lacZ strains that enable detection of a wide spectrum of mutational events.Semantic proximity Read ↗

Mismatch repair in Escherichia coli enhances instability of (CTG)n triplet repeats from human hereditary diseases.Semantic proximity Read ↗

Alternative DNA structure formation in the mutagenic human c-MYC promoter.Semantic proximity Read ↗

Low abundance of Escherichia coli microsatellites is associated with an extremely low mutation rate.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.