Article
Genetic instability within monotonous runs of CpG sequences in Escherichia coli.
Genetics - 1 Jul 1995
Bichara M, Schumacher S, Fuchs R P
Abstract excerpt
Genetic information can be altered by base substitutions, frameshift mutations, and addition or deletion of nucleotides. Deletions represent an important class of genetic aberration occurring at DNA sequences where it is often possible to predict the existence of intermediates of mutation. Instab...
Topics
- Base Sequence
- Colorectal Neoplasms
- DNA Transposable Elements
- DNA, Bacterial
- Escherichia coli
- Frameshift Mutation
- Humans
- Molecular Sequence Data
- Mutation
- Nucleic Acid Conformation
- Plasmids
- Repetitive Sequences, Nucleic Acid
- Sequence Deletion
- Time Factors