Article
Distance and pairing effects on the brownDominant heterochromatic element in Drosophila.
Genetics - 1 Jul 1995
Henikoff S, Jackson J M, Talbert P B
Abstract excerpt
We examined the behavior of the brownDominant (bwD) heterochromatic insertion moved to different locations relative to centric heterochromatin. Effects were measured as the degree of silencing of a wild-type brown eye pigment gene by bwD across a tandem duplication. A series of X-ray-induced effects were recovered at high frequency. Cis-acting enhancers were obtained by relocation of the duplication closer to...
Topics
- Alleles
- Animals
- Chromosome Mapping
- Crosses, Genetic
- Drosophila
- Female
- Genes, Dominant
- Heterochromatin
- Heterozygote
- Male
- Mutagenesis
- Suppression, Genetic
