Article
Pairing-dependent mislocalization of a Drosophila brown gene reporter to a heterochromatic environment.
Genetics - 1 Jun 1999
Sass G L, Henikoff S
Abstract excerpt
We describe the precise positioning of a reporter gene within heterochromatin where it may be silenced. A transposition of the 59E-60A region into pericentric heterochromatin ensnares distal 59E-60A via somatic pairing. The frequency with which a brown (bw) reporter gene in 59E is silenced is influenced by chromosomal configurations. Silencing occurs only when the bw+ reporter is unpaired due to heterozygosity...
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