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Article

The epigenome of evolving Drosophila neo-sex chromosomes: dosage compensation and heterochromatin formation.

PLoS biology - 1 Nov 2013

Zhou Qi, Ellison Christopher E, Kaiser Vera B, Alekseyenko Artyom A, Gorchakov Andrey A, Bachtrog Doris

Abstract excerpt

Sex chromosomes originated from autosomes but have evolved a highly specialized chromatin structure. Drosophila Y chromosomes are composed entirely of silent heterochromatin, while male X chromosomes have highly accessible chromatin and are hypertranscribed as a result of dosage compensation. Here, we dissect the molecular mechanisms and functional pressures driving heterochromatin formation and dosage...

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Identifiers

PMID: 24265597
DOI: 10.1371/journal.pbio.1001711
PMCID: PMC3825665

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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