Two new immunogenetic polymorphisms of the apoB gene and their effect on serum lipid levels and responses to changes in dietary fat intake.

doi:10.1161/01.atv.15.9.1287

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Article

Two new immunogenetic polymorphisms of the apoB gene and their effect on serum lipid levels and responses to changes in dietary fat intake.

Arteriosclerosis, thrombosis, and vascular biology - 1 Sept 1995

Ilmonen M, Heliö T, Bütler R, Palotie A, Pietinen P, Huttunen J K, Tikkanen M J

Abstract excerpt

In previous studies, apoB polymorphisms have been shown to modify serum lipid responses to changes in dietary fat intake. The functionally important apoB DNA change or changes underlying these effects have, however, remained unknown. Using a single-strand conformation polymorphism analysis-based screening method, we identified two previously unreported apoB polymorphisms located close to each other in the 5'...

Topics

Alleles
Apolipoproteins B
Asparagine
Base Sequence
Dietary Fats
Female
Finland
Gene Frequency
Genetic Variation
Genotype
Humans

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Lipids

Male

Molecular Sequence Data

Pedigree

Polymerase Chain Reaction

Polymorphism, Single-Stranded Conformational

Serine

Source

Open in PubMed

Identifiers

PMID: 7670940
DOI: 10.1161/01.atv.15.9.1287

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-7670940-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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